Scary Science: Ondansetron Safety in Pregnancy-Two Opposing Results From the Same Danish Registry.
نویسنده
چکیده
While perceived safe in pregnancy, several recent studies raise concerns about both fetal and maternal safety of ondansetron. Until more data are available, it should not be a first-line medication for morning sickness.
منابع مشابه
Linkage between the Danish National Health Service Prescription Database, the Danish Fetal Medicine Database, and other Danish registries as a tool for the study of drug safety in pregnancy
A linked population-based database is being created in Denmark for research on drug safety during pregnancy. It combines information from the Danish National Health Service Prescription Database (with information on all prescriptions reimbursed in Denmark since 2004), the Danish Fetal Medicine Database, the Danish National Registry of Patients, and the Medical Birth Registry. The new linked dat...
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Background & Aims: Due to the importance of a suitable treatment for nausea and vomiting during pregnancy and reducing maternal and fetal complications, and the beneficial effect of Ondansetron in the treatment of nausea and vomiting compared with promethazine, this study was performed. Methods: In this case-control study, 60 pregnant women under 20 weeks of gestation with hyperemesis gravidaru...
متن کاملOff-Label Use of Ondansetron in Pregnancy in Western Australia
AIMS Nausea and vomiting of pregnancy is the most common medical condition in pregnancy. There is an increasing trend to prescribe ondansetron although its safety for use in pregnancy has not been established. METHODS Exposed pregnancies were all births in Western Australia, 2002-2005, where the mother was dispensed ondansetron under the Australian Pharmaceutical Benefits Scheme, compared wit...
متن کاملINFLAMMATION AND INFLAMMATORY BOWEL DISEASE Birth outcome in women exposed to 5-aminosalicylic acid during pregnancy: a Danish cohort study
Background: 5-Aminosalicylic acid (5-ASA) preparations are the firstline drugs in the treatment of inflammatory bowel disease. Data on the safety of these drugs in pregnancy are sparse. Aims: To examine the risk of adverse birth outcome in women who were prescribed 5-ASA drugs during pregnancy. Patients: Women were included in the study if they were prescribed 5-ASA drugs immediately before or ...
متن کاملBirth outcome in women exposed to 5-aminosalicylic acid during pregnancy: a Danish cohort study.
BACKGROUND 5-Aminosalicylic acid (5-ASA) preparations are the firstline drugs in the treatment of inflammatory bowel disease. Data on the safety of these drugs in pregnancy are sparse. AIMS To examine the risk of adverse birth outcome in women who were prescribed 5-ASA drugs during pregnancy. PATIENTS Women were included in the study if they were prescribed 5-ASA drugs immediately before or...
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عنوان ژورنال:
- Therapeutic drug monitoring
دوره شماره
صفحات -
تاریخ انتشار 2014